126216-46-4Relevant articles and documents
Amination with N-Benzyloxycarbonyl-3-Phenyloxaziridine as a Route to Sensitive Chiral α-Hydrazino Acids: Synthesis of L-Hydrazino Serine
Niederer, Daniel A.,Kapron, James T.,Vederas, John C.
, p. 6859 - 6862 (2007/10/02)
N-Cbz-3-phenyloxaziridine can be generated in a two step process.This is a new reagent for direct electrophilic N-amination of chiral α-amino acids and their derivatives which affords the corresponding hydrazino acids protected with a readily removable N-Cbz group.Application of this methodology to a facile synthesis of L-hydrazino serine, a potentially useful biological tool, is described.