1262198-07-1

Basic information

• Product Name: 3-BroMo-2,6-difluoroaniline, 96%
• Synonyms: 3-BroMo-2,6-difluoroaniline, 96%
• CAS NO: 1262198-07-1
• Molecular Formula: C₆H₄BrF₂N
• Molecular Weight: 208.0034664
• Mol File: 1262198-07-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 203.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.788±0.06 g/cm3(Predicted)
• PKA: 0.74±0.10(Predicted)
• CAS DataBase Reference: 3-BroMo-2,6-difluoroaniline, 96%(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BroMo-2,6-difluoroaniline, 96%(1262198-07-1)
• EPA Substance Registry System: 3-BroMo-2,6-difluoroaniline, 96%(1262198-07-1)

Safety Data

• HazardClass: 6.1
• Hazardous Substances Data: 1262198-07-1(Hazardous Substances Data)

Upstream product

• 5509-65-9 2,6-difluoroaniline 
• 3896-29-5 N-(2,6-difluorophenyl)acetamide 

Downstream Products

• 1269233-08-0 N-(2,6-difluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propane-1-sulfonamide 
• 1269233-07-9 N-(3-bromo-2,6-difluorophenyl) propane-1-sulfonamide 
• 1383745-30-9 C₆H₂BrF₂N₃ 
• 1383745-32-1 C₁₄H₉BrF₂N₄O 
• 1383745-39-8 C₂₇H₁₉F₂N₅O 
• 1383745-34-3 C₁₄H₁₁F₂N₅O 
• 1383744-99-7 C₂₀H₁₃F₄N₅O₃S 

Relevant articles and documents

PROTEIN KINASE MKK4 INHIBITORS FOR PROMOTING LIVER REGENERATION OR REDUCING OR PREVENTING HEPATOCYTE DEATH

The invention relates to pyrazolo-pyridine compounds which inhibit mitogen-activated protein kinase kinase 4 (MKK4) and in particular, selectively inhibit MKK4 over protein kinases JNK1 and MKK7. The compounds are useful for promoting liver regeneration or reducing or preventing hepatocyte death. They are further useful for treating osteoarthritis or rheumatoid arthritis, or CNS-related diseases.

NEW TRIAZOLYLPHENYL SULFONAMIDES AS SERINE/THREONINE KINASE INHIBITORS

The present invention encompasses compounds of general formula (I) wherein the groups R2 to R4, A,X and m are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain compounds of this kind and their use as medicaments.

Compounds and Compositions as Protein Kinase Inhibitors

The present invention provides compounds of Formula I or II: wherein R1, R1b, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds of Formula (I) or (II) and pharmaceutical compositions thereof are useful for the treatment of B-Raf-associated diseases.