126229-90-1

Upstream product

• 188685-33-8 methyl [3,4,5-tris(n-octadecan-1-yloxy)]benzoate 
• 112-89-0 1-Bromooctadecane 
• 831-61-8 Ethyl gallate 
• 149-91-7 3,4,5-trihydroxybenzoic acid 
• 1268837-82-6 C₆₃H₁₁₈O₅ 
• 99-24-1 methyl galloate 
• 121-79-9 Propyl gallate 

Downstream Products

• 1268837-86-0 C₆₇H₁₁₇NO₇ 
• 1268837-88-2 C₆₇H₁₁₉NO₅ 
• 1447447-01-9 N-ethyl-3,4,5-tris(octadecyloxy)benzamide 
• 1447447-03-1 N-(3-(ethylamino)-3-oxopropyl)-3,4,5-tris(octadecyloxy)benzamide 
• 1447447-02-0 N-(5-acetamidopentyl)-3,4,5-tris(octadecyloxy)benzamide 

Relevant academic research and scientific papers

SYNTHESIS OF OLIGONUCLEOTIDES AND RELATED COMPOUNDS

Methods of synthesizing oligonucleotides via new intermediates on a cleavable support having an azidomethyl moiety are disclosed. The method comprises multiple reaction cycles, each of which comprises sequential coupling a nucleoside or oligonucleotide su

Green-Light-Triggered Phase Transition of Azobenzene Derivatives toward Reversible Adhesives

Studies on the azobenzene derivative based phase transitions mostly rely on photoisomerization, which require a long time to spontaneously revert back. Here we show a photothermal-driven solid-to-liquid transition and fast reversion of azobenzene derivati

METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID

In this method, an oligonucleotide is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R1, Y, Base, Z, Ar, R2, R3 and n are each as defined in Claim 1]. The

Design, synthesis, and characterization of 1,3,5-Tri(1 H-benzo[d]imidazol-2-yl)benzene-based fluorescent supramolecular columnar liquid crystals with a broad mesomorphic range

A new kind of supramolecular columnar liquid crystal T-A with a broad mesomorphic range (up to 164.9 °C), good thermal stability, and strong fluorescence is designed and formed by the H-bonding between 1,3,5-tri(1H-benzo[d]imidazol-2-yl)benzene (T) and serial gallic acid derivatives (A). Two components are easily available because of simple routes, common reactions, high yields, commercial starting materials, and inexpensive catalysts. The introduction of the 1,2,3-triazole structure into component A makes the textures different and is slightly disadvantageous for the T-A complexes.

Liquid-phase RNA synthesis by using alkyl-chain-soluble support

Recent progress in the RNA therapeutics has increased demand for the synthesis of large quantities of oligoribonucleotides. The assembly of RNA oligomers relies mainly on solid-phase approaches. These allow rapid product purification and the ability to drive a target reaction to completion through the use of excess reagents. Despite the known advantages of solid-phase synthesis, some issues in the process remain to be addressed, such as low and limited scale, reagent accessibility, and the use of a very large excess of reagents. Herein, we report a highly efficient and practical method of liquid-phase synthesis of RNA oligomers by using alkyl-chain-soluble support. We demonstrate the utility of the liquid-phase method through 21-mer RNA synthesis on a gram scale. The assembly of RNA oligomers relies principally on solid-phase approaches, although some alternative methods have been developed to date. A highly efficient and practical method of liquid-phase synthesis for RNA oligomers by using an alkyl-chain-type soluble support is reported. The utility of the liquid-phase method through 21-mer RNA synthesis on a gram scale is described (see scheme). Copyright

Columnar liquid-crystalline phase from a series of symmetrical bent diphenylamine derivatives: Synthesis and characterization

A series of symmetrical bent-shaped materials with six alkoxy chains at the terminal position has been designed and synthesized. All except one exhibit columnar mesophase behavior. The mesomorphic properties of the compounds have been studied with the help of polaralizing optical microscopy (POM) and differential scanning colorimetry (DSC) experiments.

Thermomorphic system with non-fluorous phase-tagged Ru(BINAP) catalyst: Facile liquid/solid catalyst separation and application in asymmetric hydrogenation

The thermomorphic BINAP derivative 1 tagged with long alkyl chains was prepared from (S)-5,5′-diamino BINAP and applied to Ru-catalyzed asymmetric hydrogenation of β-ketoesters under homogeneous conditions in 3:1 (v/v) ethanol/ 1,4-dioxane at 60 °C with high enantioselectivity (up to 98% ee). Results indicated that the Ru(1) catalyst was easily recovered by simple cooling and precipitation and could be used for at least four cycles without any loss of enantioselectivity.

Synthesis of new type of dendritic molecule and its columnar self-assembly having a potential as molecular cavity

In this study, we synthesized the first generation aromatic polyamide dendron having one trioxyethylene chain at the top of the dendron and six octadecyl chains at the other terminals. This material forms two types of crystals, K1 and K2/

A novel protecting group for constructing combinatorial peptide libraries

3,4,5-Tris(octadecyloxy)benzyl alcohol, HO-Bzl(OC18)3, was prepared from gallic acid and stearyl bromide. Using conventional step-wise elongation, N,C-protected peptides, Fmoc - AAn - ... - AA1 - OBzl(OC18)3, were synthesized. The substituted benzyl esters were selectively cleaved by a treatment with 4 M hydrogen chloride in ethyl acetate to give Fmoc - AAn - ... - AA1 - OH and HO - Bzl(OC18)3. Thus, the substituted benzyl group is effective for the protection of C-terminal carboxyl groups in liquid-phase peptide synthesis. Because the substituted benzyl group has a moderately high molecular weight, Fmoc - AAn - ... - AA1 - OBzl(OC18)3 can be easily purified by size-exclusion chromatography; all protected peptides are eluted in the void fraction of a Sephadex LH-20 gel-filtration column. The combination of the carboxyl-protecting group Bzl(OC18)3 with simple purification by the gel-filtration gives a novel route for constructing combinatorial peptide libraries in the solution phase.

Coassembly of a hexagonal columnar liquid crystalline superlattice from polymer(s) coated with a three-cylindrical bundle supramolecular dendrimer

The synthesis and structural analysis of a polymer containing twin- dendritic benzamide side-groups (i.e. poly{N-[3,4-bis(n-dodecan-1-yloxy)- 5(1-methacryloyl-η-undecan-1-yloxy)phenyl]-3,4,5-tris(n-dodecan-1- yloxy)benzamide}) (19) are described. The disc