1262293-89-9Relevant academic research and scientific papers
Azaindole-based inhibitors of Cdc7 kinase: Impact of the Pre-DFG residue, Val 195
Tong, Yunsong,Stewart, Kent D.,Florjancic, Alan S.,Harlan, John E.,Merta, Philip J.,Przytulinska, Magdalena,Soni, Nirupama,Swinger, Kerren K.,Zhu, Haizhong,Johnson, Eric F.,Shoemaker, Alexander R.,Penning, Thomas D.
, p. 211 - 215 (2013/03/29)
To investigate the role played by the unique pre-DFG residue Val 195 of Cdc7 kinase on the potency of azaindole-chloropyridines (1), a series of novel analogues with various chloro replacements were synthesized and evaluated for their inhibitory activity
