12624-18-9 Usage
Uses
Used in Biochemical Research:
(S)-4-Formyl-2,3-dihydro-1H-azepine-2,7-dicarboxylic acid is used as a research compound for studying the role of FAD in various biological processes. Its application is crucial in understanding the mechanisms of energy production, metabolism, and the function of the electron transport chain in cells.
Used in Pharmaceutical Development:
In the pharmaceutical industry, (S)-4-Formyl-2,3-dihydro-1H-azepine-2,7-dicarboxylic acid is used as a key component in the development of drugs targeting enzymes that utilize FAD as a coenzyme. This application aids in the creation of therapies for conditions related to energy metabolism and cellular function.
Used in Diagnostics:
(S)-4-Formyl-2,3-dihydro-1H-azepine-2,7-dicarboxylic acid is employed as a diagnostic tool to assess the activity of enzymes that require FAD as a coenzyme. This application is valuable in identifying and monitoring various metabolic disorders and conditions related to energy production in cells.
Used in Enzyme Production:
In the biotechnology industry, (S)-4-Formyl-2,3-dihydro-1H-azepine-2,7-dicarboxylic acid is used as a substrate for the production of enzymes that depend on FAD. This application is essential for industrial processes that require specific enzymes for the synthesis of certain compounds or the breakdown of complex molecules.
Used in Nutritional Supplements:
(S)-4-Formyl-2,3-dihydro-1H-azepine-2,7-dicarboxylic acid is utilized as an ingredient in nutritional supplements designed to support energy production and metabolism. Its inclusion in these products aims to enhance cellular function and overall health.
Check Digit Verification of cas no
The CAS Registry Mumber 12624-18-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,6,2 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 12624-18:
(7*1)+(6*2)+(5*6)+(4*2)+(3*4)+(2*1)+(1*8)=79
79 % 10 = 9
So 12624-18-9 is a valid CAS Registry Number.
12624-18-9Relevant academic research and scientific papers
The formation of betalamic acid and muscaflavin by recombinant DOPA- dioxygenase from Amanita
Mueller, Lukas A.,Hinz, Ursula,Zryd, Jean-Pierre
, p. 567 - 569 (2007/10/03)
DOPA-dioxygenase from Amanita muscaria is known to catalyse the conversion of 3-(3,4-dihydroxyphenyl)alanine (DOPA) to betalamic acid in the key reaction of betalain biosynthesis. In this work, we re-examined the reactivity of DOPA-dioxygenase using a cDNA clone encoding active DOPA- dioxygenase the kinetic parameters of which were comparable to those of the native enzyme. Using L-DOPA as a substrate, the enzyme catalysed the formation of two products. In addition to betalamic acid, the enzyme also catalysed the formation of muscaflavin, a compound that occurs naturally in A. muscaria and in mushrooms of the Hygrocybe family but not in the betalain- containing plants of the order Caryophyllales. Muscaflavin arises by a 2,3- extradiol cleavage of DOPA, whereas betalamic acid is the product of a 4,5- cleavage. Our results indicate that the recombinant enzyme has both 2,3- and 4,5-dioxygenase activity, and do not support the prevailing view that the two compounds are produced by two distinct enzymes.
Colouring Matters from Fly Agaric, VII. - Constitution and Synthesis of Muscaflavin
Barth, Hubert,Burger, Guenther,Doepp, Heinrike,Kobayashi, Makoto,Musso, Hans
, p. 2164 - 2179 (2007/10/02)
The constitution of the yellow dihydroazepine amino acid muscaflavin, isolated from mushrooms, has been established as 1a.This was confirmed by a biomimetic synthesis of the DL ester 1b, starting from pyridylalanine 12a via the glutaconic dialdehyde inter
