1262405-90-2

Upstream product

• 106-24-1 Geraniol 
• 6138-90-5 trans-geranyl bromide 
• 139-85-5 3,4-dihydroxybenzaldehyde 

Downstream Products

• 1262405-86-6 PJ₁₄₇₁ 
• 1262405-87-7 PJ₁₄₇₂ 
• 1262405-88-8 PJ₁₄₇₄ 
• 1262405-92-4 PJ₁₄₇₅ 
• 1262405-93-5 PJ₁₄₇₆ 
• 1262405-94-6 PJ₁₄₇₇ 
• 1262405-91-3 (E)-3-(3-(dimethylamino)propoxy)-4-(3,7-dimethylocta-2,6-dienyloxy)benzaldehyde 
• 1655506-94-7 (E)-3-(3-(diethylamino)propoxy)-4-(3,7-dimethylocta-2,6-dienyloxy)benzaldehyde 
• 1655506-95-8 (E)-4-(3,7-dimethylocta-2,6-dienyloxy)-3-(3-(pyrrolidin-1-yl)propoxy)benzaldehyde 
• 1655506-96-9 (E)-4-(3,7-dimethylocta-2,6-dienyloxy)-3-(3-(piperidin-1-yl)propoxy)benzaldehyde 
• 1655506-97-0 (E)-4-(3,7-dimethylocta-2,6-dienyloxy)-3-(3-(4-methylpiperidin-1-yl)propoxy)benzaldehyde 
• 1655506-98-1 (E)-4-(3,7-dimethylocta-2,6-dienyloxy)-3-(3-morpholinopropoxy)benzaldehyde 
• 1655506-99-2 (E)-4-(3,7-dimethylocta-2,6-dienyloxy)-3-(3-(4-methylpiperazin-1-yl)propoxy)benzaldehyde 

Relevant academic research and scientific papers

Synthesis and bioactivity of diketopiperazine PJ147 and its derivatives from Gliocladium sp. YUP08

Concise total synthesis of diketopiperazine PJ147, obtained from mycelium of Gliocladium sp. YUP08, has been achieved in seven steps with 43.5% overall yield. Biological evaluation of PJ147 exhibited strong inhibiting activity against A375-S2, Hela, P388, A-549, HL-60, and BEL-7420 cell lines. Thus, eight derivatives of PJ147 with high water solubility were also synthesized to facilitate the in vivo bioassay of this kind of diketopiperazines. 2014