1262423-81-3Relevant articles and documents
Asymmetric iron-catalyzed hydrosilane reduction of ketones: Effect of zinc metal upon the absolute configuration
Inagaki, Tomohiko,Ito, Akihiro,Ito, Jun-Ichi,Nishiyama, Hisao
, p. 9384 - 9387 (2010)
Just a little bit: The 1/FeCl2 complex was activated in the presence of Zn and exhibited catalytic activity for the hydrosilane reduction of ketones to give the S-configured alcohol. In contrast, the mixed-catalyst system of 1 and Fe(OAc)2 provides the R enantiomer. This approach provides both enantiomers from a single chiral source by the addition of a small amount of Zn. Copyright