126245-85-0Relevant academic research and scientific papers
"COLD" SYNTHESIS OF A NEW ANTIDEPRESSANT DRUG S 3344
Vaccher, Claude,Berthelot, Pascal,Flouquet, Nathalie,Debaert, Michel
, p. 2049 - 2060 (2007/10/02)
A "cold" synthetic route to 7-(4-fluorobenzylamino)-8-methylnonanoic acid, a new antidepressant drug, is reported.This method can be used to obtain the tritium labelled compound in C8-C9 position.The synthesis involves introduction of double bond on the aliphatic chain, reduction of this and hydrolysis in alkaline medium of the ester function.
