1262515-97-8

Basic information

• Product Name: (R,R,E,E)-3-(n-benzyloxycarbonylamino)-4-[N(3')-(2'',4''-hexadienoyl)-2',2'-dimethyl-1',3'-oxazolidin-5'-yl]butanoic acid
• Synonyms: (R,R,E,E)-3-(n-benzyloxycarbonylamino)-4-[N(3')-(2'',4''-hexadienoyl)-2',2'-dimethyl-1',3'-oxazolidin-5'-yl]butanoic acid
• CAS NO: 1262515-97-8
• Molecular Weight: 430.501
• Mol File: 1262515-97-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R,R,E,E)-3-(n-benzyloxycarbonylamino)-4-[N(3')-(2'',4''-hexadienoyl)-2',2'-dimethyl-1',3'-oxazolidin-5'-yl]butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R,R,E,E)-3-(n-benzyloxycarbonylamino)-4-[N(3')-(2'',4''-hexadienoyl)-2',2'-dimethyl-1',3'-oxazolidin-5'-yl]butanoic acid(1262515-97-8)
• EPA Substance Registry System: (R,R,E,E)-3-(n-benzyloxycarbonylamino)-4-[N(3')-(2'',4''-hexadienoyl)-2',2'-dimethyl-1',3'-oxazolidin-5'-yl]butanoic acid(1262515-97-8)

Safety Data

• Hazardous Substances Data: 1262515-97-8(Hazardous Substances Data)

Upstream product

• 2614-88-2 sorbinyl chloride 
• 181772-66-7 3''-pentyl (R,E)-4-[2,2-dimethyl-N(3')-tert-butoxycarbonyl-1',3'-oxazolidin-5'-yl]but-2-enoate 
• 181772-74-7 3''-pentyl (R,R,R)-3-[N-benzyl-N-(α-methylbenzyl)amino]-4-[2',2';-dimethyl-N(3')-tert-butoxycarbonyl-1',3'-oxazolidin-5'-yl]butanoate 
• 1262515-96-7 methyl (R,R,E,E)-3-(N-benzyloxycarbonylamino)-4-[2',2'-dimethyl-N(3')-(2,4-hexadienoyl)-1',3'-oxazolidin-5'-yl]butanoate 
• 141734-42-1 methyl (R,R,E,E)-3-(N-benzyloxycarbonylamino)-5-hydroxy-6-[N-(2',4'-hexadienoyl)amino]hexanoate 
• 1262515-95-6 C₁₅H₂₂N₂O₅*ClH 
• 1262515-94-5 3'-pentyl (R,R)-3-(N-benzyloxycarbonylamino)-4-[N(3')-tert-butoxycarbonyl-2',2'-dimethyl-1',3-oxazolidin-5'-yl]butanoate 
• 1262515-93-4 3'-pentyl (R,R)-3-amino-4-[2',2-dimethyl-N(3')-tert-butoxycarbonyl-1',3'-oxazolidin-5'-yl]butanoate 

Downstream Products

• 111337-86-1 2'-amidinoethyl (R,R,E,E)-3-amino-5-hydroxy-6-[N-(2'',4''-hexadienoyl)amino]butanamide 

Relevant articles and documents

Asymmetric syntheses of (+)-negamycin, (+)-3-epi-negamycin and sperabillin C via lithium amide conjugate addition

The chemo- and enantioselective reduction of ethyl 4-chloroacetoacetate and the diastereoselective conjugate addition of enantiopure lithium N-benzyl-N-(α-methylbenzyl)amide to an α,β-unsaturated ester have been used as the key steps in the total asymmetric syntheses of (+)-negamycin (in 13 steps and 24% overall yield), (+)-3-epi-negamycin (in 13 steps and 10% overall yield) and sperabillin C (in 17 steps and 13% overall yield) from commercially available starting materials.