1262516-53-9 Usage
Uses
Used in Pharmaceutical Research and Development:
(1R,2R)-1,2-diphenyl-2-(piperidin-1-yl)ethanamine is used as a research compound for exploring its interactions with biological receptors or binding sites due to its diphenyl group. Its presence in pharmaceutical research is attributed to the potential for developing new drugs that leverage its structural features and chiral properties.
Used in Drug Discovery:
(1R,2R)-1,2-diphenyl-2-(piperidin-1-yl)ethanamine is utilized as a starting point or a building block in the design of novel pharmaceutical agents. (1R,2R)-1,2-diphenyl-2-(piperidin-1-yl)ethanamine's unique structure, including the piperidine ring and chiral centers, may offer advantages in creating drugs with specific therapeutic targets and improved efficacy.
Used in Stereochemistry Studies:
In the field of stereochemistry, (1R,2R)-1,2-diphenyl-2-(piperidin-1-yl)ethanamine serves as a model compound to investigate the effects of stereochemistry on biological activity. Understanding these effects can lead to the development of enantiomerically pure drugs with fewer side effects and better therapeutic outcomes.
Used in Medicinal Chemistry:
(1R,2R)-1,2-diphenyl-2-(piperidin-1-yl)ethanamine is applied in medicinal chemistry for the synthesis of new drug candidates. Its structural elements can be modified to create a variety of analogs with different pharmacological properties, potentially leading to the discovery of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1262516-53-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,5,1 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1262516-53:
(9*1)+(8*2)+(7*6)+(6*2)+(5*5)+(4*1)+(3*6)+(2*5)+(1*3)=139
139 % 10 = 9
So 1262516-53-9 is a valid CAS Registry Number.
1262516-53-9Relevant academic research and scientific papers
Enantioselectivity switch controlled by N,N′-di- or N,N,N′,N′-tetra-substituted chiral thiophosphorodiamide ligands, structural relatives of thioureas, in catalytic additions of diethylzinc to aldehydes
Yue, Huifeng,Huang, Huayin,Bian, Guangling,Zong, Hua,Li, Fangling,Song, Ling
, p. 170 - 180 (2014/02/14)
We have developed a series of new chiral thiophosphorodiamide ligands derived from (1R,2R)-(+)-1,2-diphenylethylenediamine, which are the structural relatives of thioureas. An investigation into their catalytic properties in asymmetric additions of diethylzinc to aldehydes has shown that N,N,N′,N′-tetra-substituted chiral thiophosphorodiamides can give (R)-secondary alcohols with up to 98% yield and 98% ee, while N,N′-di-substituted chiral thiophosphorodiamides give (S)-secondary alcohols with up to 99% yield and 97% ee values. The enantioselectivity switch is highly efficient with a broad substrate scope. We have also proposed hypothetical reaction pathways, which result in an enantioselectivity switch.
Chiral primary amine catalyzed asymmetric epoxidation of α-substituted acroleins
Li, Jiuyuan,Fu, Niankai,Zhang, Long,Zhou, Pengxin,Luo, Sanzhong,Cheng, Jin-Pei
, p. 6840 - 6849 (2011/03/19)
1,1-Disubstituted terminal alkenes remain challenging substrates in asymmetric epoxidation reactions. In this study, chiral primary amines are shown to catalyze the asymmetric epoxidation of α-substituted acroleins, a versatile type of 1,1-disubstituted t
