126257-38-3

Basic information

• Product Name: 2,3,4-Tri-O-benzyl-6-O-formyl-α-D-glucopyranosyl chloride
• Synonyms: 2,3,4-Tri-O-benzyl-6-O-formyl-α-D-glucopyranosyl chloride
• CAS NO: 126257-38-3
• Molecular Weight: 496.988
• Mol File: 126257-38-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3,4-Tri-O-benzyl-6-O-formyl-α-D-glucopyranosyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-Tri-O-benzyl-6-O-formyl-α-D-glucopyranosyl chloride(126257-38-3)
• EPA Substance Registry System: 2,3,4-Tri-O-benzyl-6-O-formyl-α-D-glucopyranosyl chloride(126257-38-3)

Safety Data

• Hazardous Substances Data: 126257-38-3(Hazardous Substances Data)

Upstream product

• 115969-49-8 2-(trimethylsilyl)ethyl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside 

Relevant articles and documents

2-(Trimethylsilyl)ethyl Glycosides. Transformation into Glycopyranosyl Chlorides

2-(Trimethylsilyl)ethyl (TMSET) glycosides were transformed in high yields into the corresponding 1-chloro sugars by treatment with 1,1-dichloromethyl methyl ether/zinc chloride.With acetyl, benzoyl, and benzyl protection of the 2-postion, the α-glycopyranosyl chloride was the major product, whereas with the 2-phthalimido sugar 13, the β-chloride 21 was obtained.The fully benzylated TMSET glucopyranoside 1 gave the α-chloro sugar 22 carrying a 6-O-formyl group whereas the partially benzylated sugars 16 and 17 gave the chloro sugars with all protecting groups intact.