1262760-10-0

Basic information

• Product Name: (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropane-1-sulfonamide
• Synonyms: (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropane-1-sulfonamide
• CAS NO: 1262760-10-0
• Molecular Weight: 612.409
• Mol File: 1262760-10-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropane-1-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropane-1-sulfonamide(1262760-10-0)
• EPA Substance Registry System: (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropane-1-sulfonamide(1262760-10-0)

Safety Data

• Hazardous Substances Data: 1262760-10-0(Hazardous Substances Data)

Upstream product

• 1262760-35-9 (R)-1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropanethiol 
• 1262760-33-7 sodium (R)-1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropane-1-sulfonate 
• 1262760-31-5 1,2-bis(1-(((R)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropyl)disulfane 
• 1262760-09-7 (R)-4-((1-iodocyclopropyl)methyl)-2,2-dimethyl-1,3-dioxolane 
• 1262760-08-6 (R)-3-(1-iodocyclopropyl)propane-1,2-diol 
• 1262760-07-5 (R)-5-((1-iodocyclopropyl)methyl)-2,2,3,3,8,8,9,9-octamethyl-4,7-dioxa-3,8-disiladecane 
• 923032-74-0 3,4-difluoro-N₂-(2-fluoro-4-iodo-phenyl)-6-methoxy-benzene-1,2-diamine 
• 1262759-99-8 (R)-1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)cyclopropane-1-sulfonyl chloride 
• 113428-57-2 (S)-(4-bromomethyl)-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 923032-37-5 (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide 

Relevant articles and documents

CHIRAL SYNTHESIS OF N-{3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMINO]-6-METHOXYPHENYL}-1-[2,3-DIHYDROXY-PROPYL]CYCLOPROPANESULFONAMIDES

The present invention relates to a novel enantioselective method of preparing (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-5 methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide, to novel intermediate compounds,