1262778-74-4Relevant articles and documents
Synthesis of active metabolites of carvedilol, an antihypertensive drug
Senthilkumar,Somannavar,Reddy, Shankar B.,Sinha, Brajesh Kumar,Narayan,Dandala, Ramesh,Mukkanti, Kaga
, p. 268 - 276 (2011/03/20)
A simple synthetic route for active metabolites of carvedilol is reported. The metabolites 4'-hydroxycarvedilol and 5'-hydroxycarvedilol have exhibited high activity for -blockade. We have disclosed syntheses of 4'-hydroxycarvedilol and 5'-hydroxycarvedil