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1262837-17-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1262837-17-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,8,3 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1262837-17:
161 % 10 = 1
So 1262837-17-1 is a valid CAS Registry Number.

1262837-17-1Downstream Products

1262837-17-1Relevant articles and documents

Synthesis and biological activities of Schiff bases of gabapentin with different aldehydes and ketones: A structure-activity relationship study

Mallesha, Lingappa,Mohana, Kikkeri N.,Veeresh, Bantal

, p. 1 - 9 (2012/05/19)

A series of novel gabapentin derivatives 6a-k and 7a-f were synthesized, and their biological activities were determined. The chemical structures were confirmed by elemental analyses, UV-visible, FT-IR, and 1H NMR spectral studies. The structure-activity relationships (SAR) for anticonvulsant and antioxidant activities were discussed. Compounds 7a-f were evaluated for their possible anticonvulsant activity by Maximal Electroshock Seizure (MES) test, and their neurotoxic effects were determined by rotorod test. Majority of the compounds were active in MES tests. Compounds 7b and 7e showed good protective effect from seizure when compared to standard drug, phenytoin (100 mg/kg). The same compounds showed no neurotoxicity at the maximum dose administered (100 mg/kg). Most of the novel compounds showed DPPH radical scavenging activity, where compounds 6f, 6j, and 7a were the best radical scavengers (IC50 was about 60 μg/ml). Springer Science+Business Media, LLC 2010.

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