1262842-26-1

Basic information

• Product Name: C₂₆H₂₃ClN₂O₄S
• Synonyms: C₂₆H₂₃ClN₂O₄S
• CAS NO: 1262842-26-1
• Molecular Weight: 494.999
• Mol File: 1262842-26-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₃ClN₂O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₃ClN₂O₄S(1262842-26-1)
• EPA Substance Registry System: C₂₆H₂₃ClN₂O₄S(1262842-26-1)

Safety Data

• Hazardous Substances Data: 1262842-26-1(Hazardous Substances Data)

Upstream product

• 223690-84-4 1-(2-Chlorophenyl)-3-(methoxycarbonyl)-1,2,3,4-tetrahydro-β-carboline 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 113247-15-7 methyl 1-(2-chlorophenyl)-9H-pyrido[3,4-b]indole-3-carboxylate 

Relevant articles and documents

Efficient and practical one-pot conversions of n- tosyltetrahydroisoquinolines into isoquinolines and of N-tosyltetrahydro-β- carbolines into β-carbolines through tandem β-elimination and aromatization

An efficient, practical, and general method for conversions of N-tosyltetrahydroisoquinolines (N-tosyl-THIQs) into isoquinolines and of N-tosyltetrahydro-β-carbolines (N-tosyl-THBCs) into β-carbolines is described. Treatment of N-tosyl-THIQs or N-tosyl-THBCs with base in dimethyl sulfoxide afforded dihydroisoquinolines or dihydro-β-carbolines as intermediates, and these were then oxidized in situ by molecular oxygen to furnish isoquinolines or β-carbolines in good to high yields. Both one-pot conversions occurred through tandem β-elimination and aromatization. An efficient method for conversions ofN-tosyltetrahydroisoquinolines (N-tosyl-THIQs) and N-tosyltetrahydro-β-carbolines (N-tosyl-THBCs) into isoquinolines and β-carbolines is described. Treatment ofN-tosyl-THIQs or N-tosyl-THBCs with base affords dihydroisoquinolines or dihydro-β- carbolines. These can be oxidized in situ by molecular oxygen to furnish isoquinolines or β-carbolines. Copyright