1262850-11-2Relevant academic research and scientific papers
Synthesis and inclusion ability of anthracene appended β- cyclodextrins: Unexpected effect of triazole linker
Mallard, Isabelle,Landy, David,Bouchemal, Nadia,Fourmentin, Sophie
, p. 35 - 42 (2011)
A new fluorescent β-cyclodextrin has been synthesized by coupling an anthracene moiety to the cyclic oligosaccharide via click chemistry. The influence of the triazole spacer was compared to the simple amino and amido linkers. While a sensing ability toward adamantan-1-ol was observed with the latter two spacers, the absence of inclusion capacity prevents the triazole modified cyclodextrin from showing any fluorescence variations. The difference in the binding behaviors studied by Isothermal Titration Calorimetry, UV-vis and fluorescence spectroscopies, was highlighted by the NOESY NMR spectra of the modified cyclodextrins: whereas a free cavity was observed for the amino and amido linkers, an important obstruction was obtained in the case of the triazole.
