1262961-79-4Relevant academic research and scientific papers
Tandem reactions leading to bicyclic pyrimidine nucleosides and benzopyran-4-ones
Fan, Xuesen,Wang, Yangyang,Qu, Yingying,Xu, Haiyun,He, Yan,Zhang, Xinying,Wang, Jianji
supporting information; experimental part, p. 982 - 985 (2011/03/22)
A novel, rapid, and efficient synthesis of bicyclic pyrimidine nucleosides and benzopyran-4-ones through oxidation of homopropargyl alcohols and subsequent isomerization, intramolecular addition of enol to allenic ketone has been developed. This methodology provides an efficient and promising approach to the structurally and pharmaceutically interesting pyrano[2,3-d]pyrimidine-2,5-dione nucleoside and benzopyran-4-one derivatives.
