1262963-97-2

Upstream product

• 135362-69-5 3-(4-methoxybenzyl)oxypropan-1-ol 
• 1262963-95-0 (2S,6R)-6-allyl-2-[2-{(4-methoxybenzyl)oxy}ethyl]-3,6-dihydro-2H-pyran 
• 1262963-96-1 (S,E)-5-hydroxy-7-{(4-methoxybenzyl)oxy}hept-2-enal 
• 380909-94-4 (3S)-1-[(4-methoxyphenyl)methoxy]hex-5-en-3-ol 
• 142860-84-2 4-(p-methoxybenzyloxy)-1,2-epoxybutane 
• 195257-62-6 (R)-2-(2-((4-methoxybenzyl)oxy)ethyl)oxirane 

Downstream Products

• 1262963-99-4 tert-butyl (R)-1-((2R,6S)-6-(2-(4-methoxybenzyloxy)ethyl)-5,6-dihydro-2H-pyran-2-yl)pent-4-en-2-yl carbonate 
• 1262963-94-9 (4S,6S)-4-(iodomethyl)-6-(((2R,6S)-6-(2-(4-methoxybenzyloxy)ethyl)-5,6-dihydro-2H-pyran-2-yl)methyl)-1,3-dioxan-2-one 
• 1262963-93-8 (S)-1-((2R,6S)-6-(2-(4-methoxybenzyloxy)ethyl)-5,6-dihydro-2H-pyran-2-yl)-3-((S)-oxiran-2-yl)propan-2-ol 
• 1262964-00-0 (2R,4R)-1-((2R,6S)-6-(2-(4-methoxybenzyloxy)ethyl)-5,6-dihydro-2H-pyran-2-yl)undecane-2,4-diol 
• 1262964-01-1 (4R,6R)-4-heptyl-6-(((2R,6S)-6-(2-(4-methoxybenzyloxy)ethyl)-5,6-dihydro-2H-pyran-2-yl)methyl)-2,2-dimethyl-1,3-dioxane 
• 1262964-04-4 C₂₁H₂₈O₆ 
• 1262964-05-5 (2R,4R)-1-((2R,6S)-6-(2-(4-methoxybenzyloxy)ethyl)-5,6-dihydro-2H-pyran-2-yl)pentane-2,4-diol 
• 1262964-06-6 (4R,6R)-4-(((2R,6S)-6-(2-(4-methoxybenzyloxy)ethyl)-5,6-dihydro-2H-pyran-2-yl)methyl)-2,2,6-trimethyl-1,3-dioxane 

Relevant academic research and scientific papers

Total Synthesis of Swinholide A: An Exposition in Hydrogen-Mediated C-C Bond Formation

Diverse hydrogen-mediated C-C couplings enable construction of the actin-binding marine polyketide swinholide A in only 15 steps (longest linear sequence), roughly half the steps required in two prior total syntheses. The redox-economy, chemo- and stereos

Iterative iodocyclization: Total synthesis of polyrhacitide B

A highly stereoselective total synthesis of polyrhacitide B is reported. Key reactions are an iodocyclization protocol developed in our group, the Maruoka asymmetric allylation, the Bartlett-Smith iodocarbonate cyclization, and iodolactonization.

Iodo-cyclizations: Novel strategy for the total syntheses of polyrhacitide a and epi-cryptocaryolone

Highly stereoselective total syntheses of polyrhacitide A and epi-cryptocaryolone have been achieved in 11 steps with high overall yield of 24% and 28%, respectively, following a recently developed strategy for the construction of trans-2,6-disubstituted-