1262995-34-5

Downstream Products

• 1266656-52-3 1-(4,4-bis(4-(trifluoromethyl)phenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol 
• 1266656-48-7 C₃₁H₃₁F₆N₃O 

Relevant academic research and scientific papers

Synthesis and SAR study of diphenylbutylpiperidines as cell autophagy inducers

A novel series of diphenylbutylpiperidines as autophagy inducers was described and extensive SAR studies resulted in derivatives (15d-e, 15i-j) with 10-fold greater activity than the lead compounds 1 and 2. Meanwhile, a new synthetic route to diphenylbutyl bromide (6) from bromobenzene and γ-butyrolactone was also reported here.

DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS

Autophagy inducing compounds, methods of their preparation and use, and kits containg said compounds are disclosed herein.