1263036-73-2Relevant academic research and scientific papers
Magnetic nanoparticles supported cinchona alkaloids for asymmetric Michael addition reaction of 1,3-dicarbonyls and maleimides
Cao, Shi-Xuan,Wang, Jia-Xi,He, Zheng-Jie
, p. 201 - 204 (2018)
Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids (quinine and quinidine) were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and elemen
Carboxymethylcellulose supported cinchonine as a recyclable catalyst for asymmetric Michael reaction
Yang, Lili,Zhou, Dapeng,Qu, Chengke,Cui, Yuanchen
, p. 1405 - 1410 (2013/01/15)
A novel cinchonine catalyst supported by carboxymethylcellulose (CMC) has been prepared with a simple approach. As-prepared CMC-supported cinchonine catalyst was used to catalyze the asymmetric Michael addition of 1,3-dicarbonyl compounds to N-benzylmaleimide at a very low loading (3 mol%). It has been found that desired adducts containing adjacent quaternary and tertiary stereocenters can be obtained in high efficiency (yield 80 %) and stereoselectivity (dr 75:25, ee 78 %). Moreover, as-prepared catalyst possesses good recyclability (at least 4 times). Springer Science+Business Media, LLC 2012.
Construction of adjacent quaternary and tertiary stereocenters by conjugate addition using polymer-supported cinchona alkaloids as catalysts
Qin, Yanyan,Yang, Gengxu,Yang, Lili,Li, Jia,Cui, Yuanchen
experimental part, p. 481 - 488 (2012/01/14)
A series of polymer-bound cinchona alkaloids has been prepared. The resultant polymer-bound cinchona alkaloids have been used as the catalysts for the asymmetric Michael reaction of 1,3-dicarbonyl compounds and N-benzylmaleimide. The corresponding asymmet
