1263094-00-3

Basic information

• Product Name: 7-Chlorokynurenic acid sodium salt
• Synonyms: 7-Chlorokynurenic acid sodium salt;7-Chloro-4-hydroxyquinoline-2-carboxylicacidsodiumsalt
• CAS NO: 1263094-00-3
• Molecular Formula: C10H5CINNaO3
• Product Categories: Glutamate
• Mol File: 1263094-00-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Desiccate at RT
• Water Solubility: Soluble in water at 100mM
• CAS DataBase Reference: 7-Chlorokynurenic acid sodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chlorokynurenic acid sodium salt(1263094-00-3)
• EPA Substance Registry System: 7-Chlorokynurenic acid sodium salt(1263094-00-3)

Safety Data

• Hazardous Substances Data: 1263094-00-3(Hazardous Substances Data)

Usage

Description

7-Chlorokynurenic acid sodium salt is a synthetic compound that acts as a potent competitive inhibitor of L-glutamate transport into synaptic vesicles. It is also known for its properties as an NMDA receptor antagonist and inhibitor of EAAT. This molecule has garnered interest in the scientific community due to its potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
7-Chlorokynurenic acid sodium salt is used as a research chemical for studying the role of L-glutamate transport and its impact on synaptic vesicles. Its ability to inhibit the transport of L-glutamate makes it a valuable tool in understanding the mechanisms of neurotransmission and synaptic function.
Used in Neurological Research:
In the field of neurological research, 7-Chlorokynurenic acid sodium salt is used as an NMDA receptor antagonist. This application is crucial for investigating the role of NMDA receptors in various neurological conditions and disorders, such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases.
Used in Neuroprotection Studies:
7-Chlorokynurenic acid sodium salt is used as a neuroprotective agent in studies aimed at understanding the mechanisms of neurodegeneration and developing potential therapeutic interventions. Its inhibitory effects on EAAT (excitatory amino acid transporter) can provide insights into the regulation of excitatory neurotransmission and its implications in neuroprotection.
Used in Drug Development:
In the drug development industry, 7-Chlorokynurenic acid sodium salt serves as a lead compound for the development of new drugs targeting L-glutamate transport, NMDA receptors, and EAAT inhibition. Its unique properties make it a promising candidate for the treatment of various neurological disorders and conditions.