1263097-07-9Relevant academic research and scientific papers
Combined heterogeneous metal/chiral amine: Multiple relay catalysis for versatile eco-friendly synthesis
Deiana, Luca,Jiang, Yan,Palo-Nieto, Carlos,Afewerki, Samson,Incerti-Pradillos, Celia A.,Verho, Oscar,Tai, Cheuk-Wai,Johnston, Eric V.,C?rdova, Armando
, p. 3447 - 3451 (2014)
Herein is described a versatile and broad synergistic strategy for expansion of chemical space and the synthesis of valuable molecules (e.g. carbocycles and heterocycles), with up to three quaternary stereocenters, in a highly enantioselective fashion from simple alcohols (31 examples, 95:5 to >99.5:0.5 e.r.) using integrated heterogeneous metal/chiral amine multiple relay catalysis and air/O2 as the terminal oxidant. A novel highly 1,4-selective heterogeneous metal/amine co-catalyzed hydrogenation of enals was also added to the relay catalysis sequences. Relay switch: A versatile strategy for expansion of chemical space and the synthesis of valuable molecules, having up to three quaternary stereocenters, in a highly enantioselective fashion from simple alcohols is described. The method employs integrated heterogeneous metal/chiral amine multiple relay catalysis and air/O2 as the terminal oxidant.
Dynamic kinetic asymmetric domino oxa-michael/carbocyclization by combination of transition-metal and amine catalysis: Catalytic enantioselective synthesis of dihydrofurans
Lin, Shuangzheng,Zhao, Gui-Ling,Deiana, Luca,Sun, Junliang,Zhang, Qiong,Leijonmarck, Hans,Cordova, Armando
supporting information; experimental part, p. 13930 - 13934 (2011/02/22)
Into the pot: A one-pot highly chemo- and enantioselective catalytic domino oxa-Michael/carbocyclization between α,β-unsaturated aldehydes and propargylic alcohols is presented. This dynamic kinetic transformation requires a combination of transition-meta
