1263197-49-4Relevant academic research and scientific papers
Catalytic enantioselective claisen rearrangements of O-allyl β-ketoesters
Uyeda, Christopher,Roetheli, Andreas R.,Jacobsen, Eric N.
supporting information; experimental part, p. 9753 - 9756 (2011/02/23)
A chiral guanidinium ion is shown to catalyze enantioselective Claisen rearrangements of O-allyl β-ketoesters in 78-87 % ee (see scheme). The pericyclic nature of the process allows products containing vicinal stereogenic centers to be accessed with both enantio- and diastereocontrol. Copyright
