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5-bromo-3-isopentyl-2-methyl-3H-imidazo[4,5-b]pyridine, also known as BRINP, is a chemical compound belonging to the imidazo[4,5-b]pyridine class. It is a potent and selective positive allosteric modulator of the GABAA receptor, a neurotransmitter receptor in the brain targeted by sedative and anxiolytic drugs. BRINP has demonstrated potential in preclinical studies for treating anxiety and other central nervous system disorders, with observed anxiolytic and anticonvulsant effects in animal models, making it a promising molecule for further research and therapeutic applications.

1263281-65-7

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1263281-65-7 Usage

Uses

Used in Pharmaceutical Industry:
5-bromo-3-isopentyl-2-methyl-3H-imidazo[4,5-b]pyridine is used as a therapeutic agent for the treatment of anxiety and other central nervous system disorders. Its mechanism of action involves modulating the GABAA receptor, which plays a crucial role in regulating neuronal excitability and is implicated in various neurological conditions.
Used in Neurological Research:
5-bromo-3-isopentyl-2-methyl-3H-imidazo[4,5-b]pyridine is used as a research tool in the study of GABAA receptor function and its role in anxiety and other neurological disorders. Its selective modulation of the receptor provides insights into the receptor's role in these conditions and helps in the development of novel therapeutic strategies.
Used in Drug Development:
5-bromo-3-isopentyl-2-methyl-3H-imidazo[4,5-b]pyridine is used as a lead compound in the development of new drugs targeting the GABAA receptor for the treatment of anxiety, epilepsy, and other neurological disorders. Its potent and selective activity makes it a valuable starting point for the design and optimization of new therapeutic agents.
Used in Preclinical Testing:
5-bromo-3-isopentyl-2-methyl-3H-imidazo[4,5-b]pyridine is used in preclinical studies to evaluate its efficacy, safety, and pharmacokinetic properties as a potential anxiolytic and anticonvulsant agent. These studies provide valuable information on its therapeutic potential and guide further development and optimization.
Used in Drug Screening:
5-bromo-3-isopentyl-2-methyl-3H-imidazo[4,5-b]pyridine is used in high-throughput screening assays to identify novel compounds with similar activity and selectivity towards the GABAA receptor. This helps in the discovery of new chemical entities with potential therapeutic applications in the treatment of anxiety and other neurological disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 1263281-65-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,3,2,8 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1263281-65:
(9*1)+(8*2)+(7*6)+(6*3)+(5*2)+(4*8)+(3*1)+(2*6)+(1*5)=147
147 % 10 = 7
So 1263281-65-7 is a valid CAS Registry Number.

1263281-65-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-3-isopentyl-2-methyl-3H-imidazo[4,5-b]pyridine

1.2 Other means of identification

Product number -
Other names 5-bromo-2-methyl-3-(3-methylbutyl)imidazo[4,5-b]pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1263281-65-7 SDS

1263281-65-7Upstream product

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