1263284-04-3 Usage
Description
Ethyl 3-AMino-2,2-difluoropropanoate Hydrochloride, also known as Ethyl 2,2-Difluoro-3-aminopropanoate Hydrochloride, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals. It is characterized by its unique molecular structure, which includes a fluorinated carbon chain and an amino group, making it a versatile building block for the development of new drugs.
Uses
Used in Pharmaceutical Synthesis:
Ethyl 3-AMino-2,2-difluoropropanoate Hydrochloride is used as a key reagent for the synthesis of pharmaceuticals, particularly in the preparation of PHD2 inhibitors. These inhibitors play a significant role in the regulation of cellular processes, such as hypoxia response and protein synthesis, which are essential for the development of novel therapeutic strategies.
Used in the Preparation of PHD2 Inhibitors:
Ethyl 3-AMino-2,2-difluoropropanoate Hydrochloride is employed as a starting material in the synthesis of Prolyl Hydroxylase Domain 2 (PHD2) inhibitors. These inhibitors are important for modulating the hypoxia-inducible factor (HIF) pathway, which is involved in various physiological and pathological processes, including angiogenesis, cell survival, and metabolism. By targeting PHD2, these inhibitors can potentially be used to treat conditions such as anemia, ischemia, and certain types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1263284-04-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,3,2,8 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1263284-04:
(9*1)+(8*2)+(7*6)+(6*3)+(5*2)+(4*8)+(3*4)+(2*0)+(1*4)=143
143 % 10 = 3
So 1263284-04-3 is a valid CAS Registry Number.
1263284-04-3Relevant articles and documents
PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
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Paragraph 0271; 0272, (2015/06/17)
There are provided compounds having a superior PHD2 inhibitory effect that are represented by general formula (I'): (in the above-mentioned general formula (I'), W, Y, R2, R3, R4, and Y4 are as described hereinabove), or pharmaceutically acceptable salts thereof.
