1263303-87-2Relevant academic research and scientific papers
Mild Synthesis of Substituted 1,2,5-Oxadiazoles Using 1,1′-Carbonyldiimidazole as a Dehydrating Agent
Neel, Andrew J.,Zhao, Ralph
supporting information, p. 2024 - 2027 (2018/04/16)
1,1′-Carbonyldiimidazole was found to induce the formation of a variety of 3,4-disubstituted 1,2,5-oxadiazoles (furazans) from the corresponding bisoximes at ambient temperature. This method enables these inherently energetic compounds to be prepared at t
1,2,5-Oxadiazole analogues of leflunomide and related compounds
Giorgis, Marta,Lolli, Marco Lucio,Rolando, Barbara,Rao, Angela,Tosco, Paolo,Chaurasia, Shilpi,Marabello, Domenica,Fruttero, Roberta,Gasco, Alberto
body text, p. 383 - 392 (2011/02/27)
A new series of compounds, structurally related to leflunomide, based on the 1,2,5-oxadiazole ring system (furazan) has been synthesised, and their ability to undergo ring scission at physiological pH to afford the corresponding cyano-oximes has been anal
