126332-13-6

Basic information

• Product Name: Dimethyl (2S,4S)-4-(p-methoxyphenylamino)-N-phthaloylglutamate
• Synonyms: Dimethyl (2S,4S)-4-(p-methoxyphenylamino)-N-phthaloylglutamate
• CAS NO: 126332-13-6
• Molecular Weight: 426.426
• Mol File: 126332-13-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Dimethyl (2S,4S)-4-(p-methoxyphenylamino)-N-phthaloylglutamate(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethyl (2S,4S)-4-(p-methoxyphenylamino)-N-phthaloylglutamate(126332-13-6)
• EPA Substance Registry System: Dimethyl (2S,4S)-4-(p-methoxyphenylamino)-N-phthaloylglutamate(126332-13-6)

Safety Data

• Hazardous Substances Data: 126332-13-6(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 160510-64-5 dimethyl (2S,4R)-N-phthaloyl-4-iodoglutamate 
• 198133-06-1 Dimethyl ester of 4-bromo-N-phthalyl-L-glutamic acid 

Downstream Products

• 1032764-47-8 (2S,4S)-1-(4-methoxyphenyl)-5-oxo-4-phthalimidoproline 
• 1032764-49-0 (2S,4S)-4-amino-1-(4-methoxyphenyl)-5-oxoproline 
• 164668-63-7 (2S,4S)-4-(p-anisidino)-2-carboxy-5-pyrrolidone 

Relevant articles and documents

Nucleophilic substitution of halogen in 4-halo derivatives of glutamic acid 3. High pressure effect on the stereochemical result of the reaction

Reactions of diastereomeric dialkyl N-phthaloyl-4-haloglutamates with para-anisidine were studied at high pressure, and an additional confirmation of the exact SN2 mechanism of the reactions was obtained. Quantitative parameters of the relative reactivity of the diastereomers were found in various solvents, which made it possible to perform the desired synthesis of products of diastereomeric substitution.