1263417-38-4

Basic information

• Product Name: 2-(bromomethyl)-5-[3-fluoro-4-(trifluoromethoxy)phenyl]pyridine
• Synonyms: 2-(bromomethyl)-5-[3-fluoro-4-(trifluoromethoxy)phenyl]pyridine
• CAS NO: 1263417-38-4
• Molecular Weight: 350.11
• Mol File: 1263417-38-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(bromomethyl)-5-[3-fluoro-4-(trifluoromethoxy)phenyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(bromomethyl)-5-[3-fluoro-4-(trifluoromethoxy)phenyl]pyridine(1263417-38-4)
• EPA Substance Registry System: 2-(bromomethyl)-5-[3-fluoro-4-(trifluoromethoxy)phenyl]pyridine(1263417-38-4)

Safety Data

• Hazardous Substances Data: 1263417-38-4(Hazardous Substances Data)

Upstream product

• 88139-91-7 (5-bromopyridin-2-yl)methanol 
• 187804-79-1 (3-fluoro-4-(trifluoromethoxy)phenyl)boronic acid 
• 1263417-37-3 {5-[3-fluoro-4-(trifluoromethoxy)phenyl]-2-pyridinyl}methanol 

Downstream Products

• 1257426-06-4 (6S)-6-({5-[3-fluoro-4-(trifluoromethoxy)phenyl]-2-pyridinyl}methoxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine 

Relevant articles and documents

NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY

The present invention relates to novel nitroimidazooxazines, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Synthesis and structure-activity relationships of aza- and diazabiphenyl analogues of the antitubercular drug (6 S)-2-nitro-6-{[4-(trifluoromethoxy) benzyl]oxy}-6,7-dihydro-5 H-imidazo[2,1-b][1,3]oxazine (PA-824)

New heterocyclic analogues of the potent biphenyl class derived from antitubercular drug PA-824 were prepared, aiming to improve aqueous solubility but maintain high metabolic stability and efficacy. The strategy involved replacement of one or both phenyl