1263469-80-2Relevant academic research and scientific papers
Access to functionalized steroid side chains via modified Julia olefination
Izgu, Enver Cagri,Burns, Aaron C.,Hoye, Thomas R.
, p. 703 - 705 (2011/04/26)
Various functionalized steroidal side chains were conveniently accessed by a modified Julia olefination strategy using a common sulfone donor and an appropriate α-branched aldehyde acceptor. For the coupling of these hindered classes of reaction partners (and in contrast to typically observed trends), the benzothiazolyl(BT)-sulfone anion gave superior outcomes compared to the phenyltetrazolyl(PT)-sulfone anion.
