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ethyl 4-(4-(tert-butyl)phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin-3-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1263485-60-4

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1263485-60-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1263485-60-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,3,4,8 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1263485-60:
(9*1)+(8*2)+(7*6)+(6*3)+(5*4)+(4*8)+(3*5)+(2*6)+(1*0)=164
164 % 10 = 4
So 1263485-60-4 is a valid CAS Registry Number.

1263485-60-4Downstream Products

1263485-60-4Relevant articles and documents

Synthesis of polyhydroquinolines and propargylamines through one-pot multicomponent reactions using an acidic ionic liquid immobilized onto magnetic Fe3O4as an efficient heterogeneous catalyst under solvent-free sonication

Nguyen, Hai Truong,Tran, Phuong Hoang,Truong, Vy Anh

, p. 25358 - 25363 (2020)

A nano-sized Fe3O4-supported Lewis acid ionic liquid catalyst for the synthesis of polyhydroquinolines and propargylamines under ultrasound irradiation has been developed. LAIL&at;MNP was synthesized from imidazolium chlorozincate(ii) ionic liquid grafted onto the surface of Fe3O4 nanoparticles and evaluated by FT-IR, TGA, SEM, Raman, TEM, ICP-OES, and EDS. The multicomponent synthesis of polyhydroquinolines and propargylamines proceeded smoothly to afford the desired products in high yields. LAIL&at;MNP can be separated easily from the reaction mixture and reused for several runs without a significant degradation in catalytic activity.

One-pot three-component synthesis of 1-amidoalkyl naphthols and polyhydroquinolines using a deep eutectic solvent: a green method and mechanistic insight

Nguyen, Vu Thanh,Nguyen, Hai Truong,Tran, Phuong Hoang

, p. 2053 - 2059 (2021/02/06)

The multicomponent synthesis of 1-amidoalkyl naphthols and polyhydroquinolines has been developed as an atom-economic procedure catalyzed by a deep eutectic solvent ([CholineCl][ZnCl2]3). The reactions proceed smoothly at low temperatures for a short reaction time without the use of toxic and volatile organic solvents. Deep eutectic solvents are capable of not only allowing multicomponent reactions to proceed in high yield but also controlling the selectivity towards desired products. The mechanistic insight was examined by HRMS (ESI) to propose a plausible mechanism. Furthermore, [CholineCl][ZnCl2]3can be recycled in up to three consecutive cycles with an insignificant loss of catalytic activity under the optimized conditions.

Higher Carbon Analogues of 1,4-Dihydropyridines as Potent TGFβ/Smad Inhibitors

Barth, Eva R.,L?ngle, Daniel,Wesseler, Fabian,Golz, Christopher,Krupp, Anna,Schade, Dennis,Strohmann, Carsten

, p. 176 - 181 (2020/01/03)

The C to Si and Ge exchange in bioactive compounds has often led to positive changes in the molecular properties, whereby Ge analogues are underrepresented. This is only possible at tetrahedral positions, and it is necessary for the analogue building bloc

Four-component synthesis of polyhydroquinolines under catalyst- and solvent-free conventional heating conditions: mechanistic studies

Mayurachayakul, Pipattra,Pluempanupat, Wanchai,Srisuwannaket, Choladda,Chantarasriwong, Oraphin

, p. 56764 - 56770 (2017/12/27)

A convenient and environmentally friendly procedure for the synthesis of polyhydroquinolines via a one-pot, four component condensation of different aromatic aldehydes with dimedone, ethyl acetoacetate and ammonium acetate has been developed. Upon heating

Identification of dihydropyridines that reduce cellular tau levels

Evans, Christopher G.,Jinwal, Umesh K.,Makley, Leah N.,Dickey, Chad A.,Gestwicki, Jason E.

supporting information; experimental part, p. 529 - 531 (2011/02/28)

A series of dihydropyridines were identified that have an effect on the accumulation of tau, an important target in Alzheimer's disease. The dihydropyridine collection was expanded using the Hantzsch multicomponent reaction to develop preliminary structur

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