126353-32-0 Usage
Chemical Properties
2-bromo-1-pyrazin-2-yl-ethanone hydrobromide is Dark Brown Solid
Uses
2-bromo-1-pyrazin-2-yl-ethanone hydrobromide is used for the synthesis of potent 6-heteroaryl-pyrrolidino-tetrahydroisoquinolines with dual histamine H3 antagonist/serotonin transporter inhibitor activity.
Check Digit Verification of cas no
The CAS Registry Mumber 126353-32-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,3,5 and 3 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 126353-32:
(8*1)+(7*2)+(6*6)+(5*3)+(4*5)+(3*3)+(2*3)+(1*2)=110
110 % 10 = 0
So 126353-32-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H5BrN2O.BrH/c7-3-6(10)5-4-8-1-2-9-5;/h1-2,4H,3H2;1H
126353-32-0Relevant articles and documents
BACE INHIBITORS
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Page/Page column 23, (2014/05/24)
The present invention provides compounds of Formula I useful as BACE inhibitors in the treatment of e.g. Alzheimer's disease : wherein A is selected from the group consisting of; of; R1 is H or F; R2 is H, -OCH3, C1-C3 alkyl,; R3 is H, -CH3, or -OCH3; and R4 is H or F; or a pharmaceutically acceptable salt thereof.
ARYL SUBSTITUTED IMIDAZO [4,5-C] PYRIDINE COMPOUNDS AS C3A RECEPTOR ANTAGONISTS
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Page/Page column 59, (2010/11/26)
Aryl substituted imidazo[4,5-c] pyridine compounds of formula (I) or pharmaceutically acceptable salt thereof are provided. These compounds are useful in pharmaceutical compositions as C3a antagonists for treating a variety of medical conditions associated with the Complement cascade.
