126362-86-5

Basic information

• Product Name: 7-Chloro-1-(2,4-dinitrophenyl)-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
• CAS NO: 126362-86-5
• Molecular Weight: 407.699
• Mol File: 126362-86-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-Chloro-1-(2,4-dinitrophenyl)-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloro-1-(2,4-dinitrophenyl)-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid(126362-86-5)
• EPA Substance Registry System: 7-Chloro-1-(2,4-dinitrophenyl)-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid(126362-86-5)

Safety Data

• Hazardous Substances Data: 126362-86-5(Hazardous Substances Data)

Upstream product

• 75073-15-3 ethyl 7-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline 3-carboxylate 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 126362-84-3 Ethyl 7-Chloro-1-(2,4-dinitrophenyl)-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 

Relevant articles and documents

SYNTHESIS OF SOME 1-ARYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACIDS AND THEIR ANTIBACTERIAL ACTIVITY

1,4-Dihydro-4-oxoquinoline-3-carboxylic acids VIIIc and VIIId were prepared via their ethyl esters VIIIa and VIIIb, which were obtained by a direct arylation of ethyl 7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate (VIa).When treated with piperazine or N-methylpiperazine compound VIIId yields VIIIe or VIIIf, respectively.Reduction of VIIId, VIIIe, and VIIIf with ferrous sulfate yields VIIIg, VIIIh, and VIIIi respectively.Diazotization and introduction of fluorine into VIIIg using hydrogen fluoride-pyridine yields VIIIj.The compounds prepared were testedfor their antimicrobial activity in vitro.