126366-28-7Relevant academic research and scientific papers
A Stereoselective Route to Enantiomeric 2-Alkyl-1,2,3,6-tetrahydropyridines
Mehmandoust, Maryam,Marazano, Christian,Das, Bhupesh C.
, p. 1185 - 1187 (1989)
A synthesis of (R)- or (S)-2-alkyl-1,2,3,6-tetrahydropyridines (1), starting from (R)- or (S)-phenylglycinol and Zincke's salt (2), and proceeding via the new oxazolidine derivative (5) as a key intermediate, is described.
Microwave-promoted synthesis of chiral pyridinium salts
Viana, Gustavo H. R.,Santos, Itamar C.,Alves, Rosemeire B.,Gil, Laurent,Marazano, Christian,Gil, Rossimiriam P. F.
, p. 7773 - 7776 (2007/10/03)
The synthesis of several chiral pyridinium salts via Zincke's reaction can be easily accomplished by domestic microwave oven irradiation. Yield enhancements, reduction of reaction time, and less racemization were observed under microwave heating when compared to conventional heating in similar conditions.
Chiral 1,2-dihydropyridines and 2,5-Dihydropyridinium Salt Equivalents. Synthesis of (+)-Anatabine and a Chiral Benzomorphane
Genisson, Yves,Mehmandoust, Maryam,Marazano, Christian,Das, Bhupesh C.
, p. 811 - 818 (2007/10/02)
Sodium borohydride reduction of readily available chiral pyridinium salts (2a-b) in alkaline medium led to 1,2-dihydropyridines (3a-b) which spontaneously cyclized to give 2,5-dihydropyridinium salt equivalents (4a-b).Use of these intermediates for a shor
PREPARATION OF NEW CHIRAL PIPERIDINE EPOXIDES
Diez, Anna,Vilaseca, Lluis,Lopez, Isabel,Rubiralta, Mario,Marazano, Christian,et al.
, p. 2139 - 2149 (2007/10/02)
The new chiral piperidine epoxides (11b), (12b), and (13b) were prepared by MCPBA oxidation of 1,2,3,6-tetrahydropyridine (5b).Compound (5b) was obtained by NaBH4 reduction of pyridinium salt (4b) derived from the Zincke-Koenig reaction of 2b and (R)-(-)-
