1263774-42-0

Basic information

• Product Name: (3R,7aR)-3-(Trichloromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxaz ol-1-one
• Synonyms: (3R,7aR)-3-(Trichloromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxaz ol-1-one;(7aR)-3-(Trichloromethyl)tetrahydropyrrolo[1,2-c]oxazol-1(3H)-one
• CAS NO: 1263774-42-0
• Molecular Formula: C7H8Cl3NO2
• Molecular Weight: 244.50292
• EINECS: -0
• Mol File: 1263774-42-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 338.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.59±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.01±0.40(Predicted)
• CAS DataBase Reference: (3R,7aR)-3-(Trichloromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxaz ol-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,7aR)-3-(Trichloromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxaz ol-1-one(1263774-42-0)
• EPA Substance Registry System: (3R,7aR)-3-(Trichloromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxaz ol-1-one(1263774-42-0)

Safety Data

• Hazardous Substances Data: 1263774-42-0(Hazardous Substances Data)

Usage

General Description

(3R,7aR)-3-(Trichloromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxaz ol-1-one is a chemical compound with the molecular formula C6H7Cl3NO2. It is a tetrahydrofuran derivative with a trichloromethyl group attached to the carbon atom. (3R,7aR)-3-(Trichloromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxaz ol-1-one has potential applications in the field of organic synthesis and medicinal chemistry due to its interesting chemical structure and potential biological activities. Its unique structure makes it a valuable target for further study to explore its potential applications in various fields.

Upstream product

• 75-87-6 chloral 
• 344-25-2 D-Prolin 

Downstream Products

• 1086395-20-1 C₁₅H₂₂N₂ 
• 960294-14-8 1,7-diazaspiro[4.5]decane-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

CYCLIC AMINE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS

There is described a novel group of cyclic amine derivative compounds, having an EP4 receptor antagonistic activity and specifically pharmaceutical compounds which are useful for the treatment or alleviation of Prostaglandin E mediated diseases. The present invention therefore relates to novel compounds which are selective antagonists of the EP4 subtype of PGE2 receptors with analgesic and antinflammatory activity, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments, inter alia for the treatment or alleviation of Prostaglandin E mediated diseases such as acute and chronic pain, osteoarthritis, inflammation-associated disorder as arthritis, rheumatoid arthritis, cancer, migraine and endometriosis.

CYCLIC AMINE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS

There is described a novel group of cyclic amine derivative compounds, having an EP4 receptor antagonistic activity and specifically pharmaceutical compounds which are useful for the treatment or alleviation of Prostaglandin E mediated diseases. The present invention therefore relates to novel compounds which are selective antagonists of the EP 4 sub type of PGE2 receptors with analgesic and antinflammatory activity, processes for their preparation, pharmaceutical compositions containing them and theiruse as medicaments, inter alia for the treatment or alleviation of Prostaglandin E mediated diseases such as acute and chronic pain, osteoarthritis, inflammation-associated disorder as arthritis, rheumatoid arthritis, cancer, migraine and endometriosis.