1263796-77-5

Basic information

• Product Name: 2-(2-hydroxy-2-methylpropanamido)-N-phenyl-N,2-dimethylpropanamide
• CAS NO: 1263796-77-5
• Molecular Weight: 278.351
• Mol File: 1263796-77-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-hydroxy-2-methylpropanamido)-N-phenyl-N,2-dimethylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-hydroxy-2-methylpropanamido)-N-phenyl-N,2-dimethylpropanamide(1263796-77-5)
• EPA Substance Registry System: 2-(2-hydroxy-2-methylpropanamido)-N-phenyl-N,2-dimethylpropanamide(1263796-77-5)

Safety Data

• Hazardous Substances Data: 1263796-77-5(Hazardous Substances Data)

Upstream product

• 594-61-6 2-methyllactic acid 
• 75755-40-7 2,2-dimethyl-3-(N-methyl-N-phenylamino)-2H-azirine 

Relevant articles and documents

Synthesis and crystal structure of 3,3,6,6-tetramethylmorpholine-2,5-dione, and its 5-monothioxo and 2,5-dithioxo derivatives

The synthesis of 3,3-dimethylmorpholine-2,5-diones 4a was achieved conveniently via the 'direct amide cyclization' of the linear precursors of type 3, which were prepared by coupling of 2,2-dimethyl-2H-azirin-3-amines 2 with 2-hydroxyalkanoic acids 1. Thionation of 4a with Lawesson's reagent yielded the corresponding 5-thioxomorpholin-2-ones 10 and morpholine-2,5-dithiones 11, respectively, depending on the reaction conditions. The structures of 3aa, 4aa, 10a, and 11a were established by X-ray crystallography. All attempts to prepare S-containing morpholine-2,5-dione analogs or thiomorpholine-2,5-diones by cyclization of corresponding S-containing precursors were unsuccessful and led to various other products. The structures of some of them have also been established by X-ray crystallography.