Basic information

Product Name: Spirolaxin
Synonyms: (3R)-5-Hydroxy-7-methoxy-3-[5-[(2R,5R,7R)-2-methyl-1,6-dioxaspiro[4.5]decane-7-yl]pentyl]isobenzofuran-1(3H)-one;Spirolaxin;Spirolaxine
CAS NO:126382-01-2
Molecular Formula: C₂₃H₃₂O₆
Molecular Weight: 404.5
EINECS: N/A
Product Categories: N/A
Mol File: 126382-01-2.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Spirolaxin(CAS DataBase Reference)
NIST Chemistry Reference: Spirolaxin(126382-01-2)
EPA Substance Registry System: Spirolaxin(126382-01-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 126382-01-2(Hazardous Substances Data)

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Usage
SDS
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126382-01-2 Usage

Uses

Used in Pharmaceutical Industry:
Spirolaxin is used as an anti-Helicobacter pylori agent for its potent antibacterial activity against H. pylori (MIC = 0.2 μg/cm3). It is particularly effective in treating infections caused by this bacterium, which is known to be a major cause of gastric ulcers and other gastrointestinal disorders.
Additionally, Spirolaxin is used as an inhibitor of cell proliferation for its ability to inhibit the growth of endothelial (BMEC, HUVEC) and tumor (LoVo, HL-60) cells in culture. This property makes it a potential candidate for applications in cancer research and therapy.
In the field of microbiology, Spirolaxin is used as a substrate for the production of hydroxylated metabolites by certain microorganisms such as B. megaterium and C. echinulate, which can further be explored for their potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 126382-01-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,3,8 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 126382-01:
(8*1)+(7*2)+(6*6)+(5*3)+(4*8)+(3*2)+(2*0)+(1*1)=112
112 % 10 = 2
So 126382-01-2 is a valid CAS Registry Number.

126382-01-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	Spirolaxine

1.2 Other means of identification

Product number	-
Other names	5-Hydroxy-7-methoxy-3-[5-(2-methyl-1,6-dioxa-spiro[4.5]dec-7-yl)-pentyl]-3H-isobenzofuran-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:126382-01-2 SDS

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