126385-55-5Relevant academic research and scientific papers
Accelerated transmetallation in Stille couplings effected by chelation to the palladium
Crisp, Geoffrey T.,Gebauer, Markus G.
, p. 3389 - 3392 (1995)
The relative reactivities of vinylstannanes 2a,b and 4a,b in a Stille coupling with vinyl bromide were studied under a variety of conditions. Vinyl bromide coupled with the sterically hindered vinylstannane 2a preferentially compared to the less hindered stannane 2b when PdCl2(CH3CN)2 was employed as a catalyst. Coordination of the nitrogen of the imine protecting group to the palladium is proposed to account for this rate acceleration.
PALLADIUM-CATALYZED SYNTHESIS OF DIENIC α-AMINO ACIDS ALLENES
Kopola, Nina,Friess, Beatrice,Cazes, Bernard,Gore, Jacques
, p. 3963 - 3966 (2007/10/02)
1,3-Dienic or styryl α-amino acid precursors 6 and 10 are easily obtained through the catalytic carbopalladation of allenes followed by the trapping of the intermediate ?-allyl complex 3 with either the anion of Schiff base 5 or of acetamidomalonate 9.
