1263941-34-9

Upstream product

• 1263941-22-5 3-bromo-2-{(2S)-1,4-dioxaspiro[4.5]dec-2-yl}prop-1-ene 
• 1263941-26-9 4-(2-{(2S)-1,4-dioxaspiro[4.5]dec-2-yl}prop-2-enyl)-2-methylthiazole 
• 1263941-30-5 4-[(1E)-2-{(2S)-1,4-dioxaspiro[4.5]dec-2-yl}prop-1-enyl]-2-methylthiazole 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1263941-46-3 (2R,3E)-3-methyl-4-(2-methylthiazol-4-yl)-1-cyanobut-3-en-2-yl (1S)-2-methoxy-2-phenyl-3,3,3-trifluoropropionate 
• 1263941-56-5 (2R,3E)-3-methyl-4-(2-methylthiazol-4-yl)-1-cyanobut-3-en-2-yl 2-methoxy-2-phenyl-3,3,3-trifluoropropionate 

Relevant academic research and scientific papers

Synthesis of epothilones molecule fragment (15R)-C13-C 21 from D-mannitol

Efficient synthesis of an epothilone molecules fragment (15R)-C 13-C21 was carried out from D-mannitol through its conversion into methyl 2,3-O-cyclohexylidene-D-glycerate followed by the cyclopropanation of the ester group with ethy