126410-85-3

Upstream product

• 82689-15-4 O-benzyl-N-(tert-butoxycarbonyl)-L-tyrosinal 
• 126410-83-1 [(S)-1-(4-Benzyloxy-benzyl)-2-hydroxy-but-3-enyl]-carbamic acid tert-butyl ester 
• 126410-84-2 Acetic acid 1-[(S)-2-(4-benzyloxy-phenyl)-1-tert-butoxycarbonylamino-ethyl]-allyl ester 
• 126410-45-5 tert-butyl (S)-{3-[4-(benzyloxy)phenyl]-1-[methoxy(methyl)amino]-1-oxo-propan-2-yl}carbamate 
• 132785-49-0 (E)-(S)-2-Benzenesulfonyl-7-(4-benzyloxy-phenyl)-6-tert-butoxycarbonylamino-hept-4-enoic acid methyl ester 
• 126410-77-3 [(E)-1-(4-Benzyloxy-benzyl)-6-hydroxy-hex-2-enyl]-carbamic acid tert-butyl ester 
• 109687-62-9 2-<(tert-butoxycarbonyl)amino>-1-<4-(phenylmethoxy)-phenyl>-6-<(2-tetrahydropyranyl)oxy>-trans-3-hexene 
• 109687-61-8 4-(phenylseleno)-1-<4-(phenylmethoxy)phenyl>-6-<(2-tetrahydropyranyl)oxy>-trans-2-hexene 
• 109687-59-4 3-(phenylseleno)-4-<(4-phenylmethoxy)phenyl>butene 
• 109687-60-7 1-(phenylseleno)-4-<(4-phenylmetoxy)phenyl>-trans-2-butene 
• 5544-60-5 4-(benzyloxy)benzyl bromide 

Downstream Products

• 126410-86-4 [(E)-(S)-1-(4-Benzyloxy-benzyl)-6-hydroxy-hex-2-enyl]-carbamic acid tert-butyl ester 
• 126410-88-6 [(E)-(S)-1-(4-Benzyloxy-benzyl)-6-iodo-hex-2-enyl]-carbamic acid tert-butyl ester 
• 126410-87-5 Methanesulfonic acid (E)-(S)-7-(4-benzyloxy-phenyl)-6-tert-butoxycarbonylamino-hept-4-enyl ester 

Relevant academic research and scientific papers

A stereocontrolled synthesis of trans-allylic amines

The palladium catalyzed coupling of allylic acetates with nucleophiles generates urethane protected trans-allylic amines with exceptionally high stereoselectivity.

New Approaches to the Synthesis of trans-Alkene Isosteres of Dipeptides

Two new syntheses of protected dipeptide analogues bearing a trans carbon-carbon double bond in place of the amide linkage are reported.One route is a linear synthesis employing the rearrangement of an allylic selenide to a protected allylic amine.The second route is convergent and uses the Julia olefin synthesis in a key step.The latter route is fully stereocontrolled and has been used to prepare protected trans-alkene isosteres of the dipeptides TyrAla, PhePhe, LeuPhe, and LeuLeu.