1264166-23-5Relevant academic research and scientific papers
Synthesis of Indenones via Palladium-Catalyzed Ligand-Free Carbonylation
Song, Juan,Sun, Haisen,Sun, Wei,Fan, Yuxuan,Li, Cui,Wang, Haotian,Xiao, Kang,Qian, Yan
, p. 5521 - 5527 (2019)
A palladium-catalyzed ligand-free carbonylation reaction has been developed for the synthesis of indenones. Under CO atmosphere, this cascade reaction proceeded smoothly to provide the desired indenones in moderate to excellent yields with good functional-group compatibility. The mechanistic investigations suggested the in situ formation of palladium nanoparticles and this transformation was driven by a controlled reaction sequence of alkyne insertion followed by carbonylation and annulation to form the indenone framework. (Figure presented.).
Synthetic method of indanone and derivatives thereof
-
Paragraph 0058-0059; 0062-0065; 0066-0071, (2019/08/01)
The invention discloses a synthesis method of indanone and derivatives thereof, which comprises the following steps: adding a dialkyl acetylene compound, a palladium catalyst, an additive and an inorganic base into a dry reaction container together, and r
Regioselective arylation and alkynylation of 2,3-dibromo-1h-inden-1-one by Suzukii-Miyaura and Sonogashira cross-coupling reactions
Khera, Rasheed Ahmad,Hussain, Munawar,Hung, Nguyen Thai,Eleya, Nadi,Feist, Holger,Villinger, Alexander,Langer, Peter
experimental part, p. 469 - 482 (2012/05/04)
Suzukii-Miyaura reactions of 2,3-dibromo-1H-inden-1-one afforded a wide range of arylated 1H-inden-1-ones. Sonogashira cross-coupling reactions gave alkynylated indenones. The reactions proceeded with very good regioselectivity in the less sterically hind
Site-selective Suzuki-Miyaura reactions of 2,3-dibromo-1H-inden-1-one
Hussain, Munawar,Hung, Nguyen Thai,Khera, Rasheed Ahmed,Villinger, Alexander,Langer, Peter
experimental part, p. 184 - 187 (2011/02/26)
The first transition metal-catalyzed cross-coupling reactions of 2,3-dibromo-1H-inden-1-one are reported. The Suzuki-Miyaura reaction of 2,3-dibromo-1H-inden-1-one with 2 equiv of arylboronic acid gave 2,3-diaryl-1H-inden-1-ones. The reaction with 1 equiv of arylboronic acid gave 2-bromo-3-aryl-1H-inden-1-ones with very good site-selectivity. The one-pot reaction of 2,3-dibromo-1H-inden-1-one with two different arylboronic acids afforded 2,3-diaryl-1H-inden-1-ones containing two different terminal aryl groups.
