1264166-38-2Relevant academic research and scientific papers
Regioselective arylation and alkynylation of 2,3-dibromo-1h-inden-1-one by Suzukii-Miyaura and Sonogashira cross-coupling reactions
Khera, Rasheed Ahmad,Hussain, Munawar,Hung, Nguyen Thai,Eleya, Nadi,Feist, Holger,Villinger, Alexander,Langer, Peter
experimental part, p. 469 - 482 (2012/05/04)
Suzukii-Miyaura reactions of 2,3-dibromo-1H-inden-1-one afforded a wide range of arylated 1H-inden-1-ones. Sonogashira cross-coupling reactions gave alkynylated indenones. The reactions proceeded with very good regioselectivity in the less sterically hind
Site-selective Suzuki-Miyaura reactions of 2,3-dibromo-1H-inden-1-one
Hussain, Munawar,Hung, Nguyen Thai,Khera, Rasheed Ahmed,Villinger, Alexander,Langer, Peter
experimental part, p. 184 - 187 (2011/02/26)
The first transition metal-catalyzed cross-coupling reactions of 2,3-dibromo-1H-inden-1-one are reported. The Suzuki-Miyaura reaction of 2,3-dibromo-1H-inden-1-one with 2 equiv of arylboronic acid gave 2,3-diaryl-1H-inden-1-ones. The reaction with 1 equiv of arylboronic acid gave 2-bromo-3-aryl-1H-inden-1-ones with very good site-selectivity. The one-pot reaction of 2,3-dibromo-1H-inden-1-one with two different arylboronic acids afforded 2,3-diaryl-1H-inden-1-ones containing two different terminal aryl groups.
