126422-14-8

Basic information

• Product Name: 2-Phenyl-β-carboline-4-carboxylic acid
• Synonyms: 2-Phenyl-β-carboline-4-carboxylic acid
• CAS NO: 126422-14-8
• Molecular Weight: 288.305
• Mol File: 126422-14-8.mol

Chemical Properties

• CAS DataBase Reference: 2-Phenyl-β-carboline-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenyl-β-carboline-4-carboxylic acid(126422-14-8)
• EPA Substance Registry System: 2-Phenyl-β-carboline-4-carboxylic acid(126422-14-8)

Safety Data

• Hazardous Substances Data: 126422-14-8(Hazardous Substances Data)

Upstream product

• 126422-02-4 Ethyl 2-phenyl-β-carboline-4-carboxylate 
• 126421-91-8 5-phenyl-[1,2,4]triazine-3-carboxylic acid ethyl ester 

Downstream Products

• 91944-01-3 3-phenyl-9H-pyrido[3,4-b]indole 

Relevant articles and documents

Indole as a Dienophile in Inverse Electron Demand Diels-Alder Reactions: Reactions with 1,2,4-Triazines and 1,2-Diazines

Indole reacts with 1,2,4-triazines in the absence of solvent or in the presence of limited amounts of solvent to produce β- or γ-carbolines, benzonaphthyridines, or the noncyclized 3-indoles.The combined yields of cycloadducts with tricarbalkoxytriazines exceeds 90 percent, with the production of γ-carbolines exceeding 80 percent.The regiochemistry of the adduct and the ratio of the products is determined mainly by electronic effects of the triazine substituents.Indole also ungergoes a cyclocondensation reaction with tetramethyl 1,2-diazine-3,4,5,6-tetracarboxylate to give trimethyl 5H-6-oxophenanthridine-2,3,4-tricarboxylate.