1264273-54-2Relevant academic research and scientific papers
Inhibition of COX-1 activity and COX-2 expression by 3-(4′- geranyloxy-3′-methoxyphenyl)-2-trans propenoic acid and its semi-synthetic derivatives
Genovese, Salvatore,Curini, Massimo,Gresele, Paolo,Corazzi, Teresa,Epifano, Francesco
, p. 5995 - 5998 (2011)
Oxyprenylated naturally occurring cinnamic acids displayed efficient and promising biological activities. Aim of this study was to characterize the effects of 3-(4′-geranyl-3′-methoxy)phenyl-2-trans propenoic acid and its selected semi-synthetic analogues
Measuring method for measuring and using a kit or flagment autoantibody autoantibody or fragments thereof, and their azoxystrobin deriv., azoxystrobin
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Paragraph 0066, (2016/10/20)
PROBLEM TO BE SOLVED: To provide a method for measuring the levels of an azoxystrobin as a fungicide left in samples such as of farm products or processed products. SOLUTION: An antibody specific to azoxystrobin is obtained by using a composite, as an immunogen, of an azoxystrobin derivative and a polymeric compound. The method for assaying azoxystrobin using such an antibody is provided. An assay kit therefor is prepared. COPYRIGHT: (C)2011,JPOandINPIT
Topical anti-inflammatory activity of boropinic acid and its natural and semi-synthetic derivatives
Epifano, Francesco,Sosa, Silvio,Tubaro, Aurelia,Marcotullio, M. Carla,Curini, Massimo,Genovese, Salvatore
supporting information; experimental part, p. 769 - 772 (2011/03/18)
Boropinic acid is a natural isopentenyloxycinnamic acid extracted from the aerial parts of Boronia pinnata Sm. (Rutaceae) with soybean 5-lipoxygenase inhibitory activity. In this paper the topical anti-inflammatory activity of boropinic acid and some of its natural and semi-synthetic derivatives was evaluated using the Croton oil ear test in mice as a model of acute inflammation. Some of the tested compounds (15, 17, 19, 20) revealed an effect comparable (ID50 = 0.18 ÷ 0.72 μmol/cm2) to that of the reference drug indomethacin (ID50 = 0.23 μmol/cm 2), a non-steroidal anti-inflammatory drug.
