126429-07-0Relevant academic research and scientific papers
Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives
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, (2008/06/13)
A process for preparing a D-threo compound of the formula wherein R, and R1 have the meanings shown in the description, via protection of both the secondary hydroxy and the amino group of a corresponding D-threo 1-(phenyl)-2-amino-1,3-propanediol, fluorination of the protected compound and treatment of the thus obtained compound to afford a D-threo compound of the formula (II).
Process for preparing oxazoline compounds
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, (2008/06/13)
A novel process for regioselectively preparing oxazoline compounds is disclosed. The process utilizes an amino alcohol, a cyano compound, a base and a dihydric alcohol solvent, a polyhydric alcohol solvent or mixtures thereof.
Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds
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, (2008/06/13)
Replacement with fluorine of the primary hydroxy group of 1-phenyl-2-amino-1,3-propanediol compounds wherein the secondary hydroxy group and the amino group have been suitably protected. The reaction is carried out with an inorganic fluoride in a poly
