1264294-79-2Relevant academic research and scientific papers
Discovery of structurally novel, potent and orally efficacious GPR119 agonists
Alper, Phil,Azimioara, Mihai,Cow, Christopher,Mutnick, Daniel,Nikulin, Victor,Michellys, Pierre-Yves,Wang, Zhiliang,Reding, Esther,Paliotti, Michael,Li, Jing,Bao, Dingjiu,Zoll, Jocelyn,Kim, Young,Zimmerman, Matthew,Groessel, Todd,Tuntland, Tove,Joseph, Sean B.,McNamara, Peter,Seidel, H. Martin,Epple, Robert
, p. 2383 - 2387 (2014/05/20)
Screening hit 5 was identified in a biochemical screen for GPR119 agonists. Compound 5 was structurally novel, displayed modest biochemical activity and no oral exposure, but was structurally distinct from typical GPR119 agonist scaffolds. Systematic opti
COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY
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, (2011/02/24)
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of GPR119.
