1264942-94-0

Basic information

• Product Name: 4-(4-hydroxyazepan-1-yl)benzonitrile
• Synonyms: 4-(4-hydroxyazepan-1-yl)benzonitrile
• CAS NO: 1264942-94-0
• Molecular Weight: 216.283
• Mol File: 1264942-94-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-hydroxyazepan-1-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-hydroxyazepan-1-yl)benzonitrile(1264942-94-0)
• EPA Substance Registry System: 4-(4-hydroxyazepan-1-yl)benzonitrile(1264942-94-0)

Safety Data

• Hazardous Substances Data: 1264942-94-0(Hazardous Substances Data)

Upstream product

• 478832-21-2 4-hydroxy-hexahydro-1H-azepine-1-carboxylic acid 1,1-dimethylethyl ester 
• 1194-02-1 4-fluorobenzonitrile 
• 1159823-34-3 azepan-4-ol hydrochloride salt 

Downstream Products

• 1264941-46-9 4-[4-(1-methyl-6-oxo-1,6-dihydro-[4,4']bipyrimidinyl-2-yloxy)azepan-1-yl]benzonitrile 

Relevant articles and documents

PYRIMIDONE DERIVATIVES USED AS TAU PROTEIN KINASE 1 INHIBITORS

A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein Z represents nitrogen atom or C-X; X represents hydrogen atom or fluorine atom; R1 is hydrogen atom or a C1 -C3 alkyl group; L represents single bond or a C1 -C6 alkylene group which may be substituted; Y represents single bond, sulfur atom, oxygen atom, NH, or the like; R2 represents hydrogen atom or a cyclic group which may be substituted, which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of tau protein kinase 1 such as a neurodegenerative diseases (e.g. Alzheimer disease).