126497-31-2Relevant academic research and scientific papers
PREPARATION AND FACILE CYCLIZATION OF 5-ALKYN-1-YLLITHIUMS
Bailey, William F.,Ovaska, Timo V.,Leipert, Thomas K.
, p. 3901 - 3904 (2007/10/02)
Primary 5-hexyn-1-yllithiums, which may be generated in virtually quantitative yield by low-temperature lithium-iodine interchange, undergo regiospecific 5-exo-dig cyclization via stereoselectively syn-addition of CH2Li to the alkyne moiety to give vinyllithiums that may be trapped with any of a variety of electrophiles to deliver functionalized cyclopentylidene-containing products.
