1265140-41-7Relevant academic research and scientific papers
Synthesis and cell transfection properties of cationic uracil-morpholino tetramer
Paul, Sibasish,Pattanayak, Sankha,Sinha, Surajit
, p. 1072 - 1076 (2014/02/14)
Synthesis and cell transfection properties of guanidinium-functionalized uracil morpholino tetramer have been reported for the first time. Due to the basic nature of guanidinium groups they remain protonated under physiological conditions. Such cationic tetramer exhibits efficient cellular uptake properties as visualized by microscopy imaging using fluorescent dye BODIPY. 7′-End of this morpholino tetramer was functionalized with an azide group for conjugation with various types of biomolecules or drugs for cellular delivery.
Synthesis and cell transfection properties of cationic uracil-morpholino tetramer
Paul, Sibasish,Pattanayak, Sankha,Sinha, Surajit
, p. 1072 - 1076 (2015/02/05)
Synthesis and cell transfection properties of guanidinium-functionalized uracil morpholino tetramer have been reported for the first time. Due to the basic nature of guanidinium groups they remain protonated under physiological conditions. Such cationic tetramer exhibits efficient cellular uptake properties as visualized by microscopy imaging using fluorescent dye BODIPY. 7′-End of this morpholino tetramer was functionalized with an azide group for conjugation with various types of biomolecules or drugs for cellular delivery.
Synthesis of 5-alkynylated uracil-morpholino monomers using Sonogashira coupling
Paul, Sibasish,Nandi, Bappaditya,Pattanayak, Sankha,Sinha, Surajit
, p. 4179 - 4183 (2012/08/28)
Sonogashira coupling of 5-iodo uracil-morpholino monomer with different terminal alkynes has been achieved for first time in good to excellent yields (67-86%). We have optimized the iodination conditions for the preparation of 5-iodo uracil-morpholino mon
