1265166-16-2Relevant academic research and scientific papers
Synthesis of multisubstituted pyrroles from doubly activated cyclopropanes using an iron-mediated oxidation domino reaction
Zhang, Zhiguo,Zhang, Wei,Li, Junlong,Liu, Qingfeng,Liu, Tongxin,Zhang, Guisheng
, p. 11226 - 11233 (2014)
An alternative route has been developed for the construction of multisubstituted pyrrole derivatives from readily available, doubly activated cyclopropanes and anilines using an iron-mediated oxidation domino reaction (i.e., sequential ring-opening, cyclization, and dehydrogenation reactions). This reaction uses readily available reactants and is tolerant of a broad range of substrates, with the desired products being formed in good to excellent yields.
Iron-catalyzed synthesis of polysubstituted pyrroles via [4C+1N] cyclization of 4-acetylenic ketones with primary amines
Wang, Yeming,Bi, Xihe,Li, Dehua,Liao, Peiqiu,Wang, Yidong,Yang, Jin,Zhang, Qian,Liu, Qun
supporting information; experimental part, p. 809 - 811 (2011/04/15)
A highly efficient iron-catalyzed approach to polysubstituted pyrroles has been developed through the [4C+1N] cyclization of 4-acetylenic ketones with primary amines, leading to the synthesis of a variety of tetra- and fully-substituted pyrroles as well a
