1265221-91-7

Upstream product

• 6504-64-9 6-chloro-9-(methoxymethyl)-9H-purine 
• 766-85-8 3-methoxy-1-iodobenzene 
• 1265221-82-6 6-chloro-9-(methoxymethyl)-2-(trimethylsilyl)-9H-purine 

Downstream Products

• 1265221-85-9 9-(methoxymethyl)-8-(3-methoxyphenyl)-2-(trimethylsilyl)-9H-purine 
• 1265221-86-0 6-iodo-9-(methoxymethyl)-8-(3-methoxyphenyl)-2-(trimethylsilyl)-9H-purine 
• 1265221-99-5 ethyl 4-(9-(methoxymethyl)-8-(3-methoxyphenyl)-2-(trimethylsilyl)-9Hpurin-6-yl)benzoate 
• 1265222-00-1 9-(methoxymethyl)-8-(3-methoxyphenyl)-6-(3-(trifluoromethyl)phenyl)-2-(trimethylsilyl)-9H-purine 
• 1265221-87-1 ethyl 4-(2-iodo-9-(methoxymethyl)-8-(3-methoxyphenyl)-9H-purin-6-yl)benzoate 
• 1265221-88-2 ethyl 4-(2-(cyclohex-2-en-1-yl)-9-(methoxymethyl)-8-(3-methoxyphenyl)-9H-purin-6-yl)benzoate 
• 1265222-06-7 ethyl 4-(2-((3-chlorophenyl)(hydroxy)methyl)-9-(methoxymethyl)-8-(3-methoxyphenyl)-9H-purin-6-yl)benzoate 
• 1265222-07-8 ethyl 4-(2-((dimethylamino)methyl)-9-(methoxymethyl)-8-(3-methoxyphenyl)-9H-purin-6-yl)benzoate 
• 1265222-08-9 ethyl 4-(9-(methoxymethyl)-8-(3-methoxyphenyl)-2-(3-(trifluoromethyl)phenyl)-9H-purin-6-yl)benzoate 
• 1265222-09-0 ethyl 4-(2-(4-bromophenyl)-9-(methoxymethyl)-8-(3-methoxyphenyl)-9Hpurin-6-yl)benzoate 
• 1265222-11-4 ethyl 4-(9-(methoxymethyl)-8-(3-methoxyphenyl)-2-(pyridin-4-yl)-9H-purin-6-yl)benzoate 

Relevant academic research and scientific papers

Trifunctionalization of the purine scaffold using Mg and Zn organometallic intermediates

Starting from an appropriate 6-chloro-2-TMS-purine derivative, a regioselective functionalization of the purine scaffold was achieved successively at positions 8, 6, and 2 via zinc and magnesium intermediates which were generated either by a direct zincat